TECHNOLOGY & PRODUCT PIPELINE

Oceanyx has identified several novel and diverse chemical series from the marine cyanobacteria-based drug discovery initiatives for treating various diseases. One of the Company’s lead molecules, largazole , is a novel and distinct class I histone deacetylase (HDAC) inhibitor, and is indicated for the treatment of cancer, bone and neurodegenerative diseases.

Another novel lead chemical series is apratoxins, which target a novel mechanism of cotranslational translocation for the inhibition of growth factors and their receptors, such as VEGF and PDGF and their receptors. Multiple novel molecules in the apratoxin class have been discovered and shown excellent anti-proliferative and anti-angiogenic activities in animal models of cancer and have the potential to treat various angiogenic disorders. In addition, to these two novel chemical series, the Company’s platform has identified several other lead chemical series targeting proteases and other targets.

Oceanyx Pipeline